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From: HubMed - mesothelioma cancer <rssfwd@rssfwd.com>
Date: Fri, Aug 1, 2008 at 4:32 PM
Subject: Hypericin lights up the way for the potential treatment of nasopharyngeal cancer by photodynamic therapy.
To: mesothelioma77@gmail.com
[1]Curr Clin Pharmacol. 2006 Sep; 1(3): 217-22
Olivo M, Du HY, Bay BH
Photodynamic therapy (PDT) involves the administration of a photosensitizer followed by light irradiation with a specific wavelength, giving rise to irreversible tissue destruction. Hypericin, a herbal extract derived from Hypericum perforatum or St. John's Wort, has minimal toxicity but exhibits potent photo-damaging effects in the presence of light. Hypericin is known to generate a high yield of singlet oxygen and other reactive oxygen species that are associated with photo-oxidative cellular damage. The application of PDT with hypericin for the treatment of cancers such as recurrent mesothelioma and skin cancer has been validated in clinical trials. This mini-review focuses on the investigative studies of hypericin as a potential photodynamic agent in the treatment of nasopharyngeal cancer (NPC) in in vitro and in vivo models. NPC is an enigmatic tumor with a multifactorial etiology and a high incidence in the populations of Southern China.
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Source: http://www.hubmed.org/display.cgi?uids=18666746
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From: HubMed - mesothelioma cancer <rssfwd@rssfwd.com>
Date: Fri, Aug 1, 2008 at 4:32 PM
Subject: Hypericin lights up the way for the potential treatment of nasopharyngeal cancer by photodynamic therapy.
To: mesothelioma77@gmail.com
[1]Curr Clin Pharmacol. 2006 Sep; 1(3): 217-22
Olivo M, Du HY, Bay BH
Photodynamic therapy (PDT) involves the administration of a photosensitizer followed by light irradiation with a specific wavelength, giving rise to irreversible tissue destruction. Hypericin, a herbal extract derived from Hypericum perforatum or St. John's Wort, has minimal toxicity but exhibits potent photo-damaging effects in the presence of light. Hypericin is known to generate a high yield of singlet oxygen and other reactive oxygen species that are associated with photo-oxidative cellular damage. The application of PDT with hypericin for the treatment of cancers such as recurrent mesothelioma and skin cancer has been validated in clinical trials. This mini-review focuses on the investigative studies of hypericin as a potential photodynamic agent in the treatment of nasopharyngeal cancer (NPC) in in vitro and in vivo models. NPC is an enigmatic tumor with a multifactorial etiology and a high incidence in the populations of Southern China.
___
Source: http://www.hubmed.org/display.cgi?uids=18666746
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Powered by [5]RssFwd, a service of [6]Blue Sky Factory, Inc