Friday, August 8, 2008

Fwd: Cancer genetics: a primer for surgeons.



---------- Forwarded message ----------
From: HubMed - breast cancer <rssfwd@rssfwd.com>
Date: Sun, Aug 3, 2008 at 8:08 AM
Subject: Cancer genetics: a primer for surgeons.
To: mesothelioma77@gmail.com


[1]Surg Clin North Am. 2008 Aug; 88(4): 681-704
Benson JR, Liau SS

Contemporary ideas of carcinogenesis envisage a series of stochastic genetic changes that confer a selective growth advantage over healthy cells. These changes collectively lead to the disruption of coordinated networks of intercellular communication and cause a fundamental change in cellular behavior, which affects processes, such as proliferation, differentiation, and apoptosis. This progressive dysregulation of cellular function implies that cancer is not a morphologic entity, but a process in which the malignant phenotype is gradually acquired.



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Source: http://www.hubmed.org/display.cgi?uids=18672136
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