Sunday, June 8, 2008

Fwd: Evaluation of the Webler-Brown model for estimating tetrachloroethylene exposure from vinyl-lined asbestos cement pipes.



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From: HubMed - asbestos cancer <rssfwd@rssfwd.com>
Date: Thu, Jun 5, 2008 at 1:36 AM
Subject: Evaluation of the Webler-Brown model for estimating tetrachloroethylene exposure from vinyl-lined asbestos cement pipes.
To: mesothelioma77@gmail.com


[1]Environ Health. 2008 Jun 2; 7(1): 24
Spence LA, Aschengrau A, Gallagher LE, Webster TF, Heeren TC, Ozonoff DM

ABSTRACT: BACKGROUND: From May 1968 through March 1980, vinyl-lined asbestos-cement (VL/AC) water distribution pipes were installed in New England to avoid taste and odor problems associated with asbestos-cement pipes. The vinyl resin was applied to the inner pipe surface in a solution of tetrachloroethylene (perchloroethylene, PCE). Substantial amounts of PCE remained in the liner and subsequently leached into public drinking water supplies. METHODS: Once aware of the leaching problem and prior to remediation (April-November 1980), Massachusetts regulators collected drinking water samples from VL/AC pipes to determine the extent and severity of the PCE contamination. This study compares newly obtained historical records of PCE concentrations in water samples (n=88) with concentrations estimated using an exposure model employed in epidemiologic studies on the cancer risk associated with PCE-contaminated drinking water. The exposure model was developed by Webler and Brown to estimate the mass of PCE delivered to subjects' residences. RESULTS: The mean and median measured PCE concentrations in the water samples were 66 and 0.5mug/L, respectively, and the range extended from non-detectable to 2432 mug/L. The model-generated concentration estimates and water sample concentrations were moderately correlated (Spearman rank correlation coefficient= 0.48, p

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Source: http://www.hubmed.org/display.cgi?uids=18518975
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