---------- Forwarded message ----------
From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Wed, Feb 20, 2008 at 5:02 AM
Subject: [A Case of Advanced Gastric Cancer Successfully Treated by Combination Therapy of S-1 and Docetaxel.]
To: mesothelioma77@gmail.com
[1]Gan To Kagaku Ryoho. 2008 Feb; 35(2): 287-290
Ikarashi S, Akiyama N, Motoyama H, Sasaki S, Ito H, Funakoshi K, Kato T, Arai F
A 70-year-old man with gastric cancer of Borrmann type 3, liver metastases and peritoneal dissemination was treated by combination therapy of S-1 and docetaxel (DOC). He received DOC intravenously at 40 mg/m(2) on day 1 and S-1 orally at 100 mg/body on day 1 to 14, repeated every 28 days. After 2 courses of treatment, a CT scan revealed improvement of the gastric wall thickness, the eminent decrease of the peritoneal fluid and the reduction of the liver metastasis. After 3 courses of treatment, the primary lesion was remarkably improved on endoscopic examination, and the tumor marker normalized after 4 courses of treatment. Toxicities included leukocytopenia (WHO grade 3), neutropenia ( grade 3), anorexia (grade 2), and nausea (grade 2). Outpatient chemotherapy was possible by reduction of dose (S-1 100--> 80 mg/body, DOC 40--> 32 mg/m2). The response was maintained on CT and endoscopic examination after 21 courses of treatment. A case of an advanced gastric cancer patient successfully treated by combination therapy of S-1 and DOC was reported.
___
Source: http://www.hubmed.org/display.cgi?uids=18281767
--
Powered by [5]RssFwd, a service of [6]Blue Sky Factory, Inc
From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Wed, Feb 20, 2008 at 5:02 AM
Subject: [A Case of Advanced Gastric Cancer Successfully Treated by Combination Therapy of S-1 and Docetaxel.]
To: mesothelioma77@gmail.com
[1]Gan To Kagaku Ryoho. 2008 Feb; 35(2): 287-290
Ikarashi S, Akiyama N, Motoyama H, Sasaki S, Ito H, Funakoshi K, Kato T, Arai F
A 70-year-old man with gastric cancer of Borrmann type 3, liver metastases and peritoneal dissemination was treated by combination therapy of S-1 and docetaxel (DOC). He received DOC intravenously at 40 mg/m(2) on day 1 and S-1 orally at 100 mg/body on day 1 to 14, repeated every 28 days. After 2 courses of treatment, a CT scan revealed improvement of the gastric wall thickness, the eminent decrease of the peritoneal fluid and the reduction of the liver metastasis. After 3 courses of treatment, the primary lesion was remarkably improved on endoscopic examination, and the tumor marker normalized after 4 courses of treatment. Toxicities included leukocytopenia (WHO grade 3), neutropenia ( grade 3), anorexia (grade 2), and nausea (grade 2). Outpatient chemotherapy was possible by reduction of dose (S-1 100--> 80 mg/body, DOC 40--> 32 mg/m2). The response was maintained on CT and endoscopic examination after 21 courses of treatment. A case of an advanced gastric cancer patient successfully treated by combination therapy of S-1 and DOC was reported.
___
Source: http://www.hubmed.org/display.cgi?uids=18281767
--
Powered by [5]RssFwd, a service of [6]Blue Sky Factory, Inc